The tie will be settled on the night, with a penalty shootout to be played if the scores are level after 90 minutes.
This season marks Widnes' best season in the competition, reaching the semi-final for the first time in the club's history with a 5-1 thrashing of Vanarama National League side Southport earlier this month.
Tommy Lawson's side currently occupy 21st in the Northern Premier League Premier Division, four points clear of bottom side Sutton Coldfield Town having played two games more.
Marine have beaten both City of Liverpool and Tranmere Rovers to progress to this stage of the competition.
However, the Widnes promontory is not particularly wide and another possible explanation is the first part derives from the Danish ved, meaning a wood and possibly referring to a tree-covered promontory.
Earlier spellings of the name have been Vidnes, Wydnes and Wydness.
On Yorfrid's death the barony of Widnes passed to that of Halton. It was extended to Fiddler's Ferry in 1762 and then in 1833 a further extension to Woodend was opened.
In the same year the St Helens and Runcorn Gap Railway was opened.
In 1847, the first chemical factory was established and the town rapidly became a major centre of the chemical industry.
The demand for labour was met by large-scale immigration from Ireland, Poland, Lithuania and Wales.
In 1890 the chemical companies making alkali by the Leblanc process combined to form the United Alkali Company, later one of the constituent companies of ICI.Tags: Adult Dating, affair dating, sex dating